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Although AREDS2 revealed that no significant decrease was observed in the risk of advanced AMD for lutein/zeaxanthin, subgroup analyses showed that for participants in the lowest quintile of dietary intake (mean = 696 µg/day), lutein/zeaxanthin exhibited protective effects against AMD progression possibly because the lutein/zeaxanthin consumption of the individuals was similar to that of other well-nourished groups [103]

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doi: 10.1016/j.tifs.2021.02.032 [DOI] [Google Scholar] 195.Reza Mozafari M, Johnson C, Hatziantoniou S, Demetzos C